Cardinal Agostino Marchetto, Apostolic Nuncio, was born on 28 August 1940, attended the schools of the Patronato Leone XIII in Vicenza, entered the seminary and was ordained a priest in the Cathedral of Vicenza on 28 June 1964, by Bishop Carlo Zinato of Vicenza.

On 31 August he was appointed titular archbishop of Astigi, with the role of Apostolic Nuncio in Madagascar and Mauritius. He received episcopal consecration on 1 November 1985 by Cardinal Sebastiano Baggio.

On 7 December 1990 he was transferred as Apostolic Nuncio to Tanzania, and on 18 May 1994 as Apostolic Nuncio in Belarus.

On 8 July 1999 he returned to the Roman Curia as an official of the Secretariat of State.

On 6 November 2001 Pope John Paul II appointed him secretary of the Pontifical Council for the Pastoral Care of Migrants and Itinerant People.

On 25 August 2010, on reaching his seventieth birthday, he retired from his position to devote himself to study, in particular the hermeneutics of the Second Vatican Council.

Pope Francis considers him the greatest expert in hermeneutics of the Second Vatican Council.

Bishop Marchetto speaks French, English and Spanish in addition to Italian.

Created and proclaimed Cardinal by Pope Francis in the consistory of 30 September 2023, of the Deaconry of  Santa Maria Goretti.